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Cancer is caused by genetic and epigenic changes that can occur randomly or due to environmental factors. Those changes result in the generation of cancer cells, which are characterized by uncontrolled growth, increased survival and the capacity to spread (metastasize). Besides cancer cell-intrinsic properties, the immune response of a patient significantly influences the survival of tumor cells.

Because of the complexity and variability of human tumors, an efficient cancer therapy requires a multimodal approach. It is crucial for the development of new therapies and the improvement of existing treatment modalities to investigate the interactions between the tumor with its micro-environment and the immune system in a multi-disciplinary fashion. The URPP "Translational Cancer Research" builds a bridge between fundamental and clinical research and fosters the communication and collaboration between research groups investigating different aspects of cancer.

Prof. Konrad Basler E-Mail

Prof. Reinhard Dummer E-Mail

Prof. Maries van den Broek E-Mail